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Section: Testing > Safety/Stability

Many of the allergens identified were fragrances and other botanicals, according to ScienceAlert, which have become a leading cause of contact dermatitis.

JAMA Letter Cautions: Most 'Natural' Skin Care Contains Allergens

A Research Letter published in JAMA Dermatology highlighted the prevalence of contact allergens in natural skin care in a study of 1,651 products on the U.S. market.

Black women could be disproportionately affected, as 60% of participants who reported using hair straighteners self-identified as Black women.

Study Connects Hair Straightener Use to Incident Uterine Cancer

Hair straightening products could be linked to higher incidences of uterine cancer, a study of nearly 34,000 women in the U.S. recently found.

'...There is currently insufficient relevant and reliable scientific data to conduct realistic ERAs and there is not enough scientific data to support sunscreen ingredient bans,' wrote the Personal Care Products Council (PCPC).

PCPC on NAS Report: 'Not Enough Data to Ban Sunscreens'

The Personal Care Products Council has released a statement responding to the National Academy of Sciences Report, "Review of Fate, Exposure, and Effects of Sunscreens in Aquatic Environments and Implications for Sunscreen Usage and Human Health."

Microbiological test methods for w/o formulas have raised questions in terms of their suitability. They also require a more critical view of the results than other product types. This first article in a two-part series reviews the limitations of such methods and options for their optimization. It also critically observes to what extent test results provide relevant information for an appropriate safety assessment. Part II, in August 2022, will explore a holistic approach to more accurately assess microbiological safety.

Determining Preservative Efficacy in W/O Formulas, Part I: Test Performance and Limitations

Microbiological test methods for w/o formulas have raised questions in terms of suitability. They also require a more critical view of the results than other product types. This first article in a two-part series reviews the limitations of such methods.

Revisions include adding “special cosmetics” and “cosmetics using new ingredients” to the key categories of sampling testing.

China Revises Cosmetic Sampling Testing Rules, Calls for Comments

The measures will focus on testing in children’s cosmetics, special cosmetics and cosmetics containing new ingredients. Measures are open to public comment through July 14, 2022.

The MyMicrobiome Standard certification for JD Jojoba Oil and JD Lusteris guarantees a microbiome-friendly product for the skin.

Jojoba Desert Ingredients Achieve MyMicrobiome Standard Certification

The MyMicrobiome Standard certification for JD Jojoba Oil and JD Lusteris is said to guarantee a microbiome-friendly product for the skin.

The sensitivity of the test indicates it could be useful as a screening tool and could contribute to research on alternative skin corrosion tests.

Researchers Develop Invertebrate Alternative In vivo Skin Corrosion Test

Work published in Environmental Pollution describes an invertebrate alternative in vivo skin corrosion test that reportedly is more sensitive to acids and alkalis than traditional skin models.

For multifunctional products such as moisturizing hand sanitizers, the sanitizer claim requires a significant reduction (2-3 log) of a microorganism population while the moisturizer claim requires data showing an increase in skin moisture.

Testing the Safety and Efficacy of Multifunctional Personal Care Products, A Primer

Multifunctional products may offer solutions to consumer challenges but as the needs of consumers grow more complex, so do their safety and efficacy testing. This article provides a primer on these considerations.

The CTPA and the U.K. cosmetic industry wants to promote the use of new approach methodologies (NAMs) as alternatives to animal testing for these vital safety requirements under other chemicals legislation, especially UK Reach.

CTPA Convenes to Progress the Use and Regulatory Acceptance of Animal Testing Alternatives

The CTPA and the U.K. cosmetic industry wants to promote the use of new approach methodologies (NAMs) as alternatives to animal testing for these vital safety requirements under other chemicals legislation, especially UK Reach.

Animal-Aid has pledged £51k to accelerate research, development and commercialization of acute toxicity tests by ethical safety testing laboratory XCellR8.

Animal Aid Funds XCellR8 for Animal-free Safety Testing

Animal-Aid has pledged £51k to accelerate the research, development and commercialization of acute toxicity tests by ethical safety testing laboratory XCellR8.

Most Rosa centifolia-derived ingredients are reported to function as skin conditioning agents in cosmetic products. Other functions associated with ingredients in this group include abrasives, antioxidants, fragrance ingredients and skin protectants.

CIR Assesses Safety of Rosa Centifolia Derivatives in Cosmetics

The CIR reviewed the safety of Rosa centifolia-derived ingredients, most of which are reported to function as skin conditioning agents in cosmetic products; read on for the findings.

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Hazard List, Harmonization, Toxicity Tests and O'Malley Appointment: ECHA Updates

This ECHA update includes one addition to the hazardous chemicals list, two proposals for harmonized classification/labeling (eugenol and tetrahydrofurfuryl methacrylate), advice for toxicity test dosing and the appointment of Shay O'Malley.

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Analyze, Optimize: Ensuring Pollution Won’t ‘Get Under Your Skin’

Anti-adhesion, removability, anti-penetration and cleansing properties were assessed in steps, as described here, to optimize formulas for effective anti-pollution protection. An approach was designed to test cosmetic ingredients and formulas for their abilities to suppress the negative effects of pollution in skin.

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Letter to Editor Questions Benzophenone Study; Author and Industry Expert Respond

A Letter to the Editor in Chemical Research in Toxicology points to flaws in a study gaining recent attention and calling for the removal of octocrylene-containing sunscreens from the market. The author responds; as does an additional industry expert, David Steinberg.

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Toxicological Evaluation of Cosmetics: A Primer

A cosmetic toxicologist can provide a clear-eyed view of the potential hazards and quantifiable risks of a product based on its composition. This primer briefly explains how.

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Research Reviews Non-penetrating Sunscreen Vehicles, Looks to Jojoba

Several "carriers for the future" were highlighted, such as lipid carriers, cyclodextrin derivatives, encapsulation approaches and non-penetrating sunscreens incorporating UV filters and jojoba oil conjugates.

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SCCS on Methyl Salicylate: Safe Within Cosmetic Limits, Weak Sensitizer

The European Scientific Committee on Consumer Safety (SCCS) recently issued its preliminary Opinion on the safety of methyl salicylate.

BASF and Givaudan collaborated to develop and validate alternative animal testing methods, leading to the first toxicology testing strategy without animals that was adopted by OECD.

BASF and Givaudan Develop First OECD-Approved Animal Test Alternatives

The OECD has, for the first time, approved a non-animal strategy to assess skin sensitization based on three tests. In addition, the Kinetic Direct Peptide Reactivity Assay was approved to predict the intensity of reactions. All tests are the results of BASF/Givaudan joint efforts.

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